Animal Models of Osteoarthritis: Challenges of Model Selection and Analysis

@article{Teeple2013AnimalMO,
  title={Animal Models of Osteoarthritis: Challenges of Model Selection and Analysis},
  author={Erin Teeple and Gregory D. Jay and Khaled A Elsaid and Braden C. Fleming},
  journal={The AAPS Journal},
  year={2013},
  volume={15},
  pages={438-446}
}
Osteoarthritis (OA) is the most common musculoskeletal disease, affecting millions of individuals worldwide. New treatment approaches require an understanding of the pathophysiology of OA and its biomechanical, inflammatory, genetic, and environmental risk factors. The purpose of animal models of OA is to reproduce the pattern and progression of degenerative damage in a controlled fashion, so that opportunities to monitor and modulate symptoms and disease progression can be identified and new… CONTINUE READING

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