Animal Models for Genetic Neuromuscular Diseases

  title={Animal Models for Genetic Neuromuscular Diseases},
  author={Mariz Vainzof and Danielle Ayub-Guerrieri and Paula C. G. Onofre and Poliana C. M. Martins and Vanessa F. Lopes and Dinorah Zilberztajn and Lucas S. Maia and Karen S. Sell and Lydia Uraco Yamamoto},
  journal={Journal of Molecular Neuroscience},
The neuromuscular disorders are a heterogeneous group of genetic diseases, caused by mutations in genes coding sarcolemmal, sarcomeric, and citosolic muscle proteins. Deficiencies or loss of function of these proteins leads to variable degree of progressive loss of motor ability. Several animal models, manifesting phenotypes observed in neuromuscular diseases, have been identified in nature or generated in laboratory. These models generally present physiological alterations observed in human… CONTINUE READING
44 Citations
39 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 44 extracted citations


Publications referenced by this paper.
Showing 1-10 of 39 references

Muscular dystrophies and protein mutations

  • M. Vainzof, M. Zatz
  • 2007
1 Excerpt

Muscular dystrophies and protein mutations. In: Uversky VN and Fink AL (Eds) Protein misfolding, aggregation, and conformational diseases. Part B: Molecular mechanisms of conformational diseases

  • M. Vainzof, M. Zatz
  • Zouhair Atassi (Ed.) Series protein reviews,
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…