J. Anim. Sci. Vol. 88, E-Suppl. 2/J. Dairy Sci. Vol. 93, E-Suppl. 1/Poult. Sci. Vol. 89, E-Suppl. 1 275 Cost-effectiveness of diagnostic strategies to identify Mycobacterium avium ssp. paratuberculosis super-shedder cows in a large dairy herd. S. S. Aly*1, R. J. Anderson2, R. H. Whitlock3, T. L. Fyock3, S. McAdams3, T. M. Byrem4, J. Jiang5, J. M. Adaska6, and I. A. Gardner1, 1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, 2California Department of Food and Agriculture, Animal Health Branch, Sacramento, 3Johne’s Research Laboratory, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, 4Antel BioSystems, Inc, Lansing, MI, 5Department of Statistics, University of California, Davis, 6California Animal Health and Food Safety Laboratory, Tulare.