Anhedonia and major depression: The role of agomelatine
@article{Giannantonio2012AnhedoniaAM, title={Anhedonia and major depression: The role of agomelatine}, author={Massimo Di Giannantonio and Giovanni Martinotti}, journal={European Neuropsychopharmacology}, year={2012}, volume={22}, pages={S505-S510} }
54 Citations
The Efficacy of Vortioxetine on Anhedonia in Patients With Major Depressive Disorder
- Psychology, MedicineFront. Psychiatry
- 2019
The unmet need in depression is to improve patient functioning and other patient-reported outcomes (e.g., quality of life), and antidepressant interventions capable of attenuating anhedonia as well as cognitive dysfunction in MDD may help in this regard.
Therapeutic Potential of Vortioxetine for Anhedonia-Like Symptoms in Depression: A Post Hoc Analysis of Data from a Clinical Trial Conducted in Japan
- Psychology, MedicineNeuropsychiatric disease and treatment
- 2022
Vortioxetine may have therapeutic potential in patients with anhedonia-like symptoms of major depressive disorder, according to a post hoc analysis of an 8-week, randomized, double-blind, placebo-controlled, phase 3 study of this multimodal antidepressant.
Anhedonia in depressed patients on treatment with selective serotonin reuptake inhibitor anti-depressant—A two-centered study in Malaysia
- Psychology, MedicineInternational journal of psychiatry in clinical practice
- 2015
Anhedonia often persists in depressed patients despite on SSRI anti-depressant treatment, and this study aims to compare the level of anhedonia between depressed patients on anti-Depressants and healthy subjects.
The Role of Agomelatine in the Treatment of Anxiety Disorders
- Psychology
- 2014
The clinical efficacy and the relative good tolerability of agomelatine may be further investigated to widen the therapeutic spectrum of ADs.
Comparative effectiveness of repeated ketamine infusions in treating anhedonia in bipolar and unipolar depression.
- Psychology, BiologyJournal of affective disorders
- 2021
Agomelatine beyond Borders: Current Evidences of Its Efficacy in Disorders Other than Major Depression
- Psychology, BiologyInternational journal of molecular sciences
- 2015
Current evidences on the role of agomelatine in disorders other than major depression are elucidated to point out a possible efficacy of such drug in the treatment of bipolar depression, anxiety disorders, alcohol dependence, migraines etc.
Effects of levomilnacipran ER on noradrenergic symptoms, anxiety symptoms, and functional impairment in adults with major depressive disorder: Post hoc analysis of 5 clinical trials.
- PsychologyJournal of affective disorders
- 2017
Efficacy and Safety of Agomelatine vs Paroxetine Hydrochloride in Chinese Han Patients with Major Depressive Disorder: A Multicentre, Double-Blind, Noninferiority, Randomized Controlled Trial
- Medicine, PsychologyJournal of clinical psychopharmacology
- 2018
Agomelatine showed equivalent antidepressant efficacy to paroxetine in treating MDD patients after 8 weeks of treatment with an acceptable safety.
Anhedonia predicts poor psychosocial functioning: Results from a large cohort of patients treated for major depressive disorder by general practitioners
- Psychology, MedicineEuropean Psychiatry
- 2017
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It is possible that anhedonia may provide the key to a more exact delineation of depressive disorders in biological research and in clinical practice, which will depend upon a more precise, cross-nationally agreed definition of the concept and the means of its assessment.
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Agomelatine in the treatment of major depressive disorder: an 8-week, multicenter, randomized, placebo-controlled trial.
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Agomelatine 25 mg/d was effective in the treatment of patients with moderate-to-severe MDD and was safe and well tolerated, although clinically notable aminotransferase elevations were observed transiently in the agomel atine 50mg/d group.