Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole.

@article{Lemke2005AnhedoniaDA,
  title={Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole.},
  author={Matthias R. Lemke and Hans Michael Brecht and Juergen Koester and P. H. Kraus and Heinz Reichmann},
  journal={The Journal of neuropsychiatry and clinical neurosciences},
  year={2005},
  volume={17 2},
  pages={214-20}
}
Anhedonia, a core symptom of depression, correlates with motor alterations in major depressive disorder and has been assumed to be frequent in depressed patients with Parkinson's disease (PD). In the present study, the authors assessed for the first time frequency of anhedonia in patients with idiopathic Parkinson's disease (N = 657) and the relationship of anhedonia and parkinsonian motor deficits during treatment with pramipexole. Mild depression was present in 47% of the patients and… CONTINUE READING

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