Angustimine and angustifolimine: two new alkaloids from Daphniphyllum angustifolium.

  title={Angustimine and angustifolimine: two new alkaloids from Daphniphyllum angustifolium.},
  author={Chuan-Rui Zhang and Cheng-Qi Fan and S. Dong and H. Liu and Wen-bin Zhou and Y. Wu and J. Yue},
  journal={Organic letters},
  volume={13 9},
  • Chuan-Rui Zhang, Cheng-Qi Fan, +4 authors J. Yue
  • Published 2011
  • Chemistry, Medicine
  • Organic letters
  • Two new alkaloids, angustimine (1) featuring an unprecedented skeleton, and angustifolimine (2) being a rare diamino Daphniphyllum alkaloid, were isolated from Daphniphyllum angustifolium. Their structures were elucidated by extensive spectroscopic analysis. The biosynthetic origin of 1 was postulated. Cytotoxic activities of 1 and 2 were tested, and all of them were inactive. 
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