Angiotensins Inhibit Cell Growth in GH3 Lactosomatotroph Pituitary Tumor Cell Culture: A Possible Involvement of the p44/42 and p38 MAPK Pathways

@inproceedings{PtasiskaWnuk2012AngiotensinsIC,
  title={Angiotensins Inhibit Cell Growth in GH3 Lactosomatotroph Pituitary Tumor Cell Culture: A Possible Involvement of the p44/42 and p38 MAPK Pathways},
  author={Dorota Ptasińska-Wnuk and Hanna Lawnicka and Slawomir A. Mucha and Jolanta Kunert-Radek and Marek Pawlikowski and Henryk Stępień},
  booktitle={TheScientificWorldJournal},
  year={2012}
}
The local renin-angiotensin system is present in the pituitary. We investigated the effects of angiotensins on GH3 lactosomatotroph cells proliferation in vitro and the involvement of p44/42 and p38 MAPK inhibitors in the growth-regulatory effects of angiotensins. Materials and Methods. Cell viability using the Mosmann method and proliferation by the… CONTINUE READING