Angiotensinogen gene variations and LV outflow obstruction in hypertrophic cardiomyopathy

@article{Wang2013AngiotensinogenGV,
  title={Angiotensinogen gene variations and LV outflow obstruction in hypertrophic cardiomyopathy},
  author={S. Wang and J. Wang and Yiming Zou and H. Wang and Rocky Hui},
  journal={Herz},
  year={2013},
  volume={39},
  pages={258-263}
}
BackgroundVariations of angiotensinogen (AGT) gene have been associated with cardiac hypertrophy. We hypothesized that AGT gene polymorphism may play a modifier role in the diversity of left ventricular outflow obstruction.MethodsThe polymorphisms of the AGT gene were genotyped in 225 patients with hypertrophic cardiomyopathy (HCM) and 243 age-and sex-matched healthy controls. The effect of the A and G alleles on the expression of the reporter gene were evaluated in vitro using dual-luciferase… CONTINUE READING

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Pediatric Cardiomyopathies.

  • Circulation research
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

Association between angiotensinogen M235T polymorphism and hypertrophic cardiomyopathy.

  • International journal of clinical and experimental medicine
  • 2015
VIEW 2 EXCERPTS
CITES METHODS

References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Mutations profile in Chinese patients with hypertrophic cardiomyopathy.

  • Clinica chimica acta; international journal of clinical chemistry
  • 2005

[Association of angiotensinogen gene M235T variant with hypertrophic cardiomyopathy].

  • Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
  • 2004

Analysis of gene-environment interaction in coronary artery disease.

  • Italian heart journal : official journal of the Italian Federation of Cardiology
  • 2002