Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients.

  title={Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients.},
  author={Thomas Urup and Signe Regner Michaelsen and Lars R\onn Olsen and Anders Toft and Ib Jarle Christensen and Kirsten Grunnet and Ole Winther and Helle Broholm and Michael Kosteljanetz and Shohreh Issazadeh-Navikas and Hans Skovgaard Poulsen and Ulrik Lassen},
  journal={Molecular oncology},
  volume={10 8},
BACKGROUND Bevacizumab combination therapy is among the most frequently used treatments in recurrent glioblastoma and patients who achieve response to bevacizumab have improved survival as well as quality of life. Accordingly, the aim of this study was to identify predictive biomarkers for bevacizumab response in recurrent glioblastoma patients. METHODS The study included a total of 82 recurrent glioblastoma patients treated with bevacizumab combination therapy whom were both response and… CONTINUE READING


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