Angiotensin type 2 receptor is important in the normal development of the ureter

@article{Hohenfellner1999AngiotensinT2,
  title={Angiotensin type 2 receptor is important in the normal development of the ureter},
  author={Katharina Hohenfellner and Tracy Earl Hunley and Carde Schloemer and Walburgis Brenner and Elizabeth B. Yerkes and Fred Zepp and John W. Brock and Valentina Kon},
  journal={Pediatric Nephrology},
  year={1999},
  volume={13},
  pages={187-191}
}
 In humans, the actions of angiotensin II are transduced through the AT1 and AT2 receptors which have recently been implicated in renal organogenesis. Polymorphisms in the human angiotensin II receptor genes have been linked to cardiovascular and nephrological disorders. In this study we evaluated 35 patients with either primary obstructive megaureter or posterior urethral valves. Each was genotyped for the A1166 AT1 polymorphism and the recently described A-1332G AT2 transition. The incidence… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 28 references

Murine double nullizygotes of angiotensin type 1 A and 1 B receptor genes have the same abnormal phenotypes as angiotensinogen nullizygotes and more ( abstract )

S Tsuchida, T Matsusaka, +5 authors I Ichikawa
J Am Soc Nephrol • 1997

The angiotensin type 2 receptor null mutant mice : a model of the diverse sepctrum of congenital urinary tract anomalies in humans ( abstract )

H Nishimura, E Yerkes, +6 authors I Ichikawa
J Am Soc Nephrol • 1997

sociation between the angiotensin type 2 receptor genotype and congenital urinary tract anomalies in two independent cohorts ( abstract )

E Yerkes, H Nishimura, +6 authors I Ichikawa
J Am Soc Nephrol • 1997

Angiotensin II type 2 receptor mediates programmed cell death.

Proceedings of the National Academy of Sciences of the United States of America • 1996

Nephrogenesis and renovascular development in angiotensinogen-deficient mice.

Laboratory investigation; a journal of technical methods and pathology • 1996

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