Angiotensin tachyphylaxis in normal and everted rings of rabbit aorta.


The development of tachyphylaxis to angiotensin II and to [1-sarcosine]angiotensin II ([Sar1]angiotensin II) was studied in rabbit aorta helical strips, normal rings and everted rings, with and without a functional endothelium. Normal rings developed tachyphylaxis to both angiotensin II and [Sar1]angiotensin II, helical strips only to [Sar1]angiotensin II… (More)


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