Angiotensin receptors as determinants of life span

@article{Cassis2009AngiotensinRA,
  title={Angiotensin receptors as determinants of life span},
  author={Paola Cassis and Sara Conti and Giuseppe Remuzzi and Ariela Benigni},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2009},
  volume={459},
  pages={325-332}
}
Angiotensin II (Ang II), the central product of renin-angiotensin system, has a role in the etiology of hypertension and in pathophysiology of cardiac and renal diseases in humans. Other functions of Ang II include effects on immune response, inflammation, cell growth and proliferation, which are largely mediated by Ang II type 1 receptor (AT1). Several experimental studies have demonstrated that Ang II acts through AT1 as a mediator of normal aging processes by increasing oxidant damage to… Expand
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