Angiotensin ii-(3–8)-hexapeptide affects motor activity, performance of passive avoidance and a conditioned avoidance response in rats

@article{Braszko1988AngiotensinIA,
  title={Angiotensin ii-(3–8)-hexapeptide affects motor activity, performance of passive avoidance and a conditioned avoidance response in rats},
  author={J. Braszko and G. Kupryszewski and B. Witczuk and K. Wi{\vs}niewski},
  journal={Neuroscience},
  year={1988},
  volume={27},
  pages={777-783}
}
  • J. Braszko, G. Kupryszewski, +1 author K. Wišniewski
  • Published 1988
  • Chemistry, Medicine
  • Neuroscience
  • Angiotensin II-(3-8)-hexapeptide, at the dose of 1 nmol given intracerebroventricularly, only slightly less than angiotensin II (the same dose and route) stimulated exploratory locomotor behaviour in an open field and electromagnetic motimeter. Both peptides considerably enhanced stereotyped behaviour produced by apomorphine and amphetamine. Angiotensin II-(3-8)-hexapeptide improved recall in a passive avoidance situation as well as angiotensin II. The 3-8 C-terminus of angiotensin II enhanced… CONTINUE READING
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