Angiotensin-converting enzyme inhibitor treatment for young normotensive diabetic subjects: a two-year trial.

@article{Chase1993AngiotensinconvertingEI,
  title={Angiotensin-converting enzyme inhibitor treatment for young normotensive diabetic subjects: a two-year trial.},
  author={H. Peter Chase and S. K. Garg and Stewart B Harris and Sandy Hoops and William E. Jackson and Daniel L. Holmes},
  journal={Annals of ophthalmology},
  year={1993},
  volume={25 8},
  pages={284-9}
}
Microangiopathy characterizes both diabetic retinopathy and nephropathy. It is currently unclear which diabetic subjects should be treated with angiotensin-converting enzyme (ACE) inhibitors. A double-blind, placebo-controlled protocol was implemented using captopril to treat subjects with Type I diabetes, early diabetic nephropathy (albumin excretion rates, 20-200 micrograms/min), and normal blood pressures. After two years, the final eye grades were improved in two treated subjects but not in… CONTINUE READING

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