Angiotensin-converting enzyme inhibition restores endothelial but not medial connexin expression in hypertensive rats.

@article{Rummery2005AngiotensinconvertingEI,
  title={Angiotensin-converting enzyme inhibition restores endothelial but not medial connexin expression in hypertensive rats.},
  author={Nicole M Rummery and T. Hilton Grayson and Caryl E. Hill},
  journal={Journal of hypertension},
  year={2005},
  volume={23 2},
  pages={317-28}
}
OBJECTIVE AND DESIGN Remodelling in the media and decreases in connexin (Cx) expression and size of endothelial cells occur in the caudal artery of spontaneously hypertensive rats (SHR). The objective of this study was to determine whether similar changes are found in the aorta and whether effects in both aorta and caudal artery are present in the pre-hypertensive period or can be reversed by antihypertensive treatment. METHODS AND RESULTS In the aorta of SHR, there was no difference in… CONTINUE READING
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