Angiotensin-converting enzyme inhibition reduces the effect of bromoethylamine-induced papillary necrosis and renal fibrosis.

@article{Garber1998AngiotensinconvertingEI,
  title={Angiotensin-converting enzyme inhibition reduces the effect of bromoethylamine-induced papillary necrosis and renal fibrosis.},
  author={Sandra L Garber and Yelena Mirochnik and Shashank S Desai and Jose A. L. Arruda and George Dunea},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1998},
  volume={9 6},
  pages={1052-9}
}
Rats injected with a single, 50-mg dose of bromoethylamine (BEA) developed papillary necrosis accompanied by sever interstitial fibrosis. At 1 mo, the creatinine clearance decreased (control 0.66 versus BEA 0.33 ml/min per 100 g body wt, P = 0.02), and the urine albumin-to-creatinine ratio increased markedly (control 0.19 versus BEA 0.51, P = 0.02). In a group of animals given the angiotensin-converting enzyme inhibitor enalapril (Enal; 100 mg/L) in their drinking water for 4 wk, beginning 1 wk… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 28 references

de long PE : A short - term antihypertensive treatment - induced fall in glomerular filtration rate predicts long - term stability of renal function

  • D ApperlooAl.deZeeuw
  • Kidney lot
  • 1997

Similar Papers

Loading similar papers…