• DOI:10.1186/1475-2840-12-36
Corpus ID: 8993204

Angiotensin-converting enzyme inhibition and food restriction restore delayed preconditioning in diabetic mice

@article{Mieren2013AngiotensinconvertingEI,
  title={Angiotensin-converting enzyme inhibition and food restriction restore delayed preconditioning in diabetic mice},
  author={G. Van der Mieren and I. Nevelsteen and A. Vanderper and W. Oosterlinck and W. Flameng and P. Herijgers},
  journal={Cardiovascular Diabetology},
  year={2013},
  volume={12},
  pages={36 - 36}
}

G. Van der Mieren, I. Nevelsteen, +3 authors P. Herijgers

Published 2013

Medicine

Cardiovascular Diabetology

BackgroundClassical and delayed preconditioning are powerful endogenous protection mechanisms against ischemia-reperfusion damage. However, it is still uncertain whether delayed preconditioning can effectively salvage myocardium in patients with co-morbidities, such as diabetes and the metabolic syndrome. We investigated delayed preconditioning in mice models of type II diabetes and the metabolic syndrome and investigated interventions to optimize the preconditioning potential.MethodsHypoxic… CONTINUE READING

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