Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: the Rotterdam Study.

@article{SayedTabatabaei2005AngiotensinCE,
  title={Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: the Rotterdam Study.},
  author={Fakhredin A. Sayed-Tabatabaei and Anna F. C. Schut and Alejandro Arias V{\'a}squez and Aida M. Bertoli-Avella and Albert Hofman and Jacqueline C. M. Witteman and Cornelia M van Duijn},
  journal={Journal of medical genetics},
  year={2005},
  volume={42 1},
  pages={26-30}
}
BACKGROUND Findings on the association between the insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme (ACE) gene and cardiovascular morbidity and mortality have been inconsistent. Considering the possible interaction between this polymorphism and smoking, we evaluated the association between ACE I/D polymorphism and myocardial infarction (MI), mortality due to coronary heart disease (CHD), and cardiovascular disease (CVD). METHODS The study was performed within the… CONTINUE READING