Angiotensin-converting enzyme gene polymorphism and risk of myocardial infarction in Colombia.

  title={Angiotensin-converting enzyme gene polymorphism and risk of myocardial infarction in Colombia.},
  author={Leonelo Enrique Bautista and Mar{\'i}a E Ardila and Germ{\'a}n Gamarra and Clara In{\'e}s Vargas and Ivan A. Arenas},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  volume={10 8},
BACKGROUND The ACE gene insertion/deletion polymorphism has been studied as a risk factor for acute myocardial infarction (AMI) in different populations with conflicting results. MATERIAL/METHODS We conducted a case-control study in first AMI cases matched by age (+/-5 years) and sex to controls with non-cardiac diseases to ascertain whether Colombian carriers of the DD genotype were at higher risk of AMI than carriers of the ID and II genotypes. Zygosity for the deletion-insertion (D-I) of… CONTINUE READING
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