Angiotensin-converting enzyme and p22(phox) polymorphisms and the risk of coronary heart disease in a low-risk Spanish population.

@article{MataBalaguer2004AngiotensinconvertingEA,
  title={Angiotensin-converting enzyme and p22(phox) polymorphisms and the risk of coronary heart disease in a low-risk Spanish population.},
  author={Trinidad Mata-Balaguer and Roberto de la Herr{\'a}n and Carmelo Ru{\'i}z-Rej{\'o}n and Manuel Ru{\'i}z-Rej{\'o}n and Manuel A. Garrido-Ramos and Fernando Ruiz-Rej{\'o}n},
  journal={International journal of cardiology},
  year={2004},
  volume={95 2-3},
  pages={145-51}
}
OBJECTIVE To evaluate the genetic contribution to myocardial infarction in a homogeneous Caucasian population (a Mediterranean Spanish population) with very low frequency of coronary heart disease (CHD). DESIGN We analyzed a total of 210 subjects, younger than 55 years, considered to be a low-risk population (104 cases of myocardial infarction and 106 control), and genotyped them (using polymerase chain reaction and sequencing) for the angiotensin-converting enzyme (ACE) insertion/deletion… CONTINUE READING