Angiotensin-converting enzyme (ACE) genotypes and disability in hospitalized older patients

  title={Angiotensin-converting enzyme (ACE) genotypes and disability in hospitalized older patients},
  author={Davide Seripa and Giulia Paroni and Maria Giovanna Matera and Carolina Gravina and Carlo Scarcelli and Michele Corritore and Luigi P. D’Ambrosio and Maria Urbano and grazia D’Onofrio and Massimiliano Copetti and Patrick Gavin Kehoe and Francesco Panza and Alberto Pilotto},
The association between angiotensin-converting enzyme (ACE) genotypes and functional decline in older adults remains controversial. To assess if ACE gene variations influences functional abilities at older age, the present study explored the association between the common ACE insertion/deletion (I/D) polymorphism and disability measured with activities of daily living (ADL) in hospitalized older patients. We analyzed the frequency of the ACE genotypes (I/I, I/D, and D/D) in a population of 2… CONTINUE READING

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