Angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms in generalized aggressive periodontitis.

@article{Grkan2009AngiotensinconvertingE,
  title={Angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms in generalized aggressive periodontitis.},
  author={Ali G{\"u}rkan and G{\"u}lnur Emingil and Buket Han Saygan and G Ekin Atilla and Timur K{\"o}se and Haluk Baylas and Afig Huseyinov Berdeli},
  journal={Archives of oral biology},
  year={2009},
  volume={54 4},
  pages={337-44}
}
AIM Host response to periodontopathic microorganisms can be modulated by genetic factors. Accumulated evidence highlighted the role of renin-angiotensin system (RAS) in inflammatory response thus potential implication of this molecular system in the pathogenesis of periodontitis can be suggested. The present study investigated common genetic variants of molecules within the RAS family namely angiotensin-converting enzyme (ACE), angiotensinogen (AGT) and angiotensin II type 1 receptor (AT1R) in… CONTINUE READING