Angiotensin Receptor–Binding Protein ATRAP/Agtrap Inhibits Metabolic Dysfunction With Visceral Obesity

@inproceedings{Maeda2013AngiotensinRP,
  title={Angiotensin Receptor–Binding Protein ATRAP/Agtrap Inhibits Metabolic Dysfunction With Visceral Obesity},
  author={Akinobu Maeda and Kouichi Tamura and Hiromichi Wakui and Toru Dejima and Masato Ohsawa and Kengo Azushima and Tomohiko Kanaoka and Kazushi Uneda and Miyuki Matsuda and Akio Yamashita and Nobuko Miyazaki and Keisuke Yatsu and Nobuhito Hirawa and Yoshiyuki Toya and Satoshi Kariya-shi Umemura},
  booktitle={Journal of the American Heart Association},
  year={2013}
}
BACKGROUND Metabolic disorders with visceral obesity have become a major medical problem associated with the development of hypertension, type 2 diabetes, and dyslipidemia and, ultimately, life-threatening cardiovascular and renal diseases. Adipose tissue dysfunction has been proposed as the cause of visceral obesity-related metabolic disorders, moving the tissue toward a proinflammatory phenotype. METHODS AND RESULTS Here we first report that adipose tissues from patients and mice with… CONTINUE READING
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