Angiotensin II type 1 receptor gene polymorphism is associated with increase of left ventricular mass but not with hypertension.

@article{Takami1998AngiotensinIT,
  title={Angiotensin II type 1 receptor gene polymorphism is associated with increase of left ventricular mass but not with hypertension.},
  author={Shinichiro Takami and Tomohiro Katsuya and Hiromi Rakugi and Naoyuki Sato and Yoshio Nakata and Atsushi Kamitani and Tetsuro Miki and Jitsuo Higaki and Toshio Ogihara},
  journal={American journal of hypertension},
  year={1998},
  volume={11 3 Pt 1},
  pages={316-21}
}
A genetic epidemiologic approach is useful to elucidate the genes responsible for hypertension. Genetic analyses of the components of the renin-angiotensin system have succeeded in showing an association between their polymorphism and hypertension. Recently, two types of angiotensin II receptor were cloned and characterized. To examine the genetic contribution of angiotensin II type 1 receptor (AT1) and type 2 receptor (AT2) genes in human essential hypertension, a case-control study was… CONTINUE READING

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