Angiotensin II subtype 1 receptor blockers and renal function.

  title={Angiotensin II subtype 1 receptor blockers and renal function.},
  author={Robert Daniel Toto},
  journal={Archives of internal medicine},
  volume={161 12},
Blood pressure reduction is the most significant factor in delaying onset and progression of renal disease. Blockade of the renin-angiotensin system (RAS) using angiotensin-converting enzyme inhibitors (ACEIs) delays renal disease progression. More recently, agents that block the RAS by preventing angiotensin II from binding to its subtype 1 receptor (ARBs) have been developed in an effort to prevent deleterious consequences of pathologic levels of angiotensin II and to reduce the adverse… CONTINUE READING