Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

Abstract

The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II) in vascular smooth muscle cells are incompletely understood but include the generation of molecules likely to affect oxidase activity. We examined the ability of Ang II to stimulate superoxide anion formation and investigated the identity of the oxidases… (More)

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@article{Griendling1994AngiotensinIS, title={Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.}, author={Kathy K. Griendling and Candace A. Minieri and Jeremy D. Ollerenshaw and Robert W. Alexander}, journal={Circulation research}, year={1994}, volume={74 6}, pages={1141-8} }