Angiotensin II stimulated expression of transforming growth factor-beta1 in cardiac fibroblasts and myofibroblasts.

Abstract

Angiotensin II (Ang II) stimulates pathologic myocardial fibrosis. Cardiac fibroblasts (CFb) and myofibroblasts mediate this response, perhaps in part by indirect production of specific cytokines. We sought to determine if Ang II could stimulate transforming growth factor-beta1 (TGF-beta1) gene expression and protein production in adult rat CFb and two… (More)

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Cite this paper

@article{Campbell1997AngiotensinIS, title={Angiotensin II stimulated expression of transforming growth factor-beta1 in cardiac fibroblasts and myofibroblasts.}, author={Scott E. Campbell and Laxmansa C. Katwa}, journal={Journal of molecular and cellular cardiology}, year={1997}, volume={29 7}, pages={1947-58} }