Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney.

@article{RuizOrtega2002AngiotensinIR,
  title={Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney.},
  author={Marta Ruiz-Ortega and Paloma Aragoncillo and O. Aguado Lorenzo and Vanesa Esteban and Julia Mart{\'i}nez Blanco and Sergio A. Mezzano and J. R. Barrueco Egido},
  journal={Kidney international. Supplement},
  year={2002},
  volume={82},
  pages={
          S12-22
        }
}
BACKGROUND Emerging evidence suggests that angiotensin II (Ang II) is not only a vasoactive peptide, but also a true cytokine that regulates cell growth, inflammation and fibrosis. Many studies have demonstrated that this peptide plays an active role in the progression of renal injury. Some of Ang II-induced effects are mediated by the production of a large array of growth factors. The aim of this study was to investigate whether Ang II could regulate the expression of cytokines and chemokines… CONTINUE READING
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