Angiotensin II receptors on human platelets.

  title={Angiotensin II receptors on human platelets.},
  author={T. J. M. Moore and Gordon H. Williams},
  journal={Circulation research},
  volume={51 3},
The investigation of the interaction between angiotensin II and its receptors in human subjects has been hampered by the inaccessibility of human tissue containing angiotensin II receptors. In order to find a more accessible angiotensin II-binding tissue, we studied angiotensin II binding to platelets in normal human volunteers. Platelet preparations purified on Ficoll: Isopaque gradients were incubated with 125I-angiotensin II (30 pm), with and without unlabeled angiotensin at 22 degrees C… CONTINUE READING


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