Angiotensin II receptors-antagonists, molecular biology, and signal transduction.

  title={Angiotensin II receptors-antagonists, molecular biology, and signal transduction.},
  author={Gowraganahalli Jagadeesh},
  journal={Indian journal of experimental biology},
  volume={36 12},
The renin-angiotensin-aldosterone system (RAAS) plays an important role in both the short-term and long-term regulation of arterial blood pressure, and fluid and electrolyte balance. The RAAS is a dual hormone system, serving as both a circulating and a local tissue hormone system (i.e., local mediator) as well as neurotransmitter or neuromediator functions in CNS. Control of blood pressure by the RAAS is exerted through multiple actions of angiotensin II, a small peptide which is a potent… CONTINUE READING


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