• Corpus ID: 1015128

Angiotensin II receptors and angiotensin II receptor antagonists.

@article{Timmermans1993AngiotensinIR,
  title={Angiotensin II receptors and angiotensin II receptor antagonists.},
  author={Pieter B.M.W.M. Timmermans and Pancras C Wong and Andrew T. Chiu and William F. Herblin and Pamela A. Benfield and David John Carini and R J Lee and Ruth R. Wexler and Jo Anne Saye and Ronald D. Smith},
  journal={Pharmacological reviews},
  year={1993},
  volume={45 2},
  pages={
          205-51
        }
}
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1,927 Citations
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Involvement of Spinal Angiotensin II System in Streptozotocin-Induced Diabetic Neuropathic Pain in Mice
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Results indicate that the expression of spinal ACE increased in STZ-induced diabetic mice, which in turn led to an increase in Ang II levels and tactile allodynia, which was shown to be mediated by AT1 receptors.
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It is provided the first evidence that aging caused a reduction of VDCC expression in rat aorta, irrespective of the rat strain, along with diminishment of the therapeutic potential of V DCC blockers.
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