Angiotensin II receptor type 1 on granulosa and thecal cells of rabbit preovulatory follicles.

@article{Fral1996AngiotensinIR,
  title={Angiotensin II receptor type 1 on granulosa and thecal cells of rabbit preovulatory follicles.},
  author={Colette F{\'e}ral and Annie Benha{\"i}m and Pierre Leymarie},
  journal={Biochimica et biophysica acta},
  year={1996},
  volume={1284 2},
  pages={
          221-6
        }
}
Specific, high-affinity angiotensin II (A II) receptors were observed on granulosa and thecal cells of preovulatory ovarian follicles from immature PMSG-treated rabbits. Scatchard analysis of 125I-[Sar1,Ile8]A II binding to freshly prepared cells was indicative of only one class of binding sites. Kd values were 0.26 +/- 0.11 nM and 0.18 +/- 0.02 nM, densities of A II receptors were 0.06 +/- 0.02 fmol/10(5) cells and 0.08 +/- 0.01 fmol/10(5) cells for granulosa and thecal cells, respectively… CONTINUE READING
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