Angiotensin II receptor blockage prevents diabetes-induced oxidative damage in rat heart.

@article{Ozdemir2009AngiotensinIR,
  title={Angiotensin II receptor blockage prevents diabetes-induced oxidative damage in rat heart.},
  author={Saime Hacer Ozdemir and Berivan Tandoğan and Nuray Nuriye Ulusu and Belma Turan},
  journal={Folia biologica},
  year={2009},
  volume={55 1},
  pages={11-6}
}
Current findings suggest a role for the angiotensin II (Ang II) signalling pathway in generation of reactive oxygen species and diabetes-induced cardiac complications. In this study we aimed to investigate the effect of angiotensin II type 1 (AT1) receptor blockage on some antioxidant enzymes such as glucose- 6-phosphate dehydrogenase (G6PD), 6-phoshogluconate dehydrogenase (6PGD), glutathione reductase (GR), glutathione-S-transferase (GST), glutathione peroxidase (GSH-Px), and catalase (CAT… CONTINUE READING

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