Angiotensin II inhibits GABAergic synaptic transmission in dorsolateral periaqueductal gray neurons.

@article{Xing2009AngiotensinII,
  title={Angiotensin II inhibits GABAergic synaptic transmission in dorsolateral periaqueductal gray neurons.},
  author={Jihong Xing and Jian Lu and Jianhua Li},
  journal={Neuroscience letters},
  year={2009},
  volume={455 1},
  pages={8-13}
}
The purpose of this study was to determine the role of angiotensin II (Ang II) in modulating inhibitory and excitatory synaptic inputs to the dorsolateral periaqueductal gray (dl-PAG). The whole cell voltage-clamp recording was performed to examine inhibitory and excitatory postsynaptic currents (IPSCs and EPSCs) of the dl-PAG neurons. Ang II, at the concentration of 2microM, decreased the frequency of miniature IPSCs from 0.83+/-0.02 to 0.45+/-0.03Hz (P<0.05) in 10 tested neurons. This did not… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Similar Papers

Loading similar papers…