Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation.

@article{Zhao2005AngiotensinII,
  title={Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation.},
  author={Yi Zhao and Anna Foryst-Ludwig and Dennis Bruemmer and Juraj Culman and Michael Bader and Thomas Unger and Ulrich Kintscher},
  journal={Journal of neurochemistry},
  year={2005},
  volume={94 5},
  pages={
          1395-401
        }
}
The angiotensin type 2 (AT2) receptor has been previously demonstrated to exert neuroprotective actions possibly by inducing neuronal cell differentiation involving neurite outgrowth. The nuclear hormone receptor peroxisome proliferator-activated receptor gamma (PPARgamma) is an important transcriptional regulator of cell differentiation. The aim of the present study was to clarify whether PPARgamma is involved in AT2-receptor-mediated morphological neuronal cell differentiation. To investigate… CONTINUE READING
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