Angiotensin II-induced calcium mobilization in oocytes by signal transfer through gap junctions.

@article{Sandberg1990AngiotensinIC,
  title={Angiotensin II-induced calcium mobilization in oocytes by signal transfer through gap junctions.},
  author={Kathryn Sandberg and M v.d. Bor and H Ji and Andrew J. Markwick and Monica A. Millan and Kevin J. Catt},
  journal={Science},
  year={1990},
  volume={249 4966},
  pages={298-301}
}
Angiotensin II (AII) stimulates rapid increases in the concentration of cytosolic calcium in follicular oocytes from Xenopus laevis. This calcium response was not present in denuded oocytes, indicating that it is mediated by AII receptors on the adherent follicular cells. The endogenous AII receptors differed in their binding properties from mammalian AII receptors expressed on the oocyte surface after injection of rat adrenal messenger RNA. Also, the calcium responses to activation of the… CONTINUE READING