Angiotensin II early regulated genes in H295R human adrenocortical cells.

  title={Angiotensin II early regulated genes in H295R human adrenocortical cells.},
  author={D. Gonz{\`a}lez Romero and Maria W Plonczynski and Gaston R Vergara and Elise P Gomez-Sanchez and Celso Enrique Gomez-Sanchez},
  journal={Physiological genomics},
  volume={19 1},
Evidence for the dysregulation of aldosterone synthesis in cardiovascular pathophysiology has renewed interest in the control of its production. Cellular mechanisms by which angiotensin II (ANG II) stimulates aldosterone synthesis in the adrenal zona glomerulosa are incompletely understood. To elucidate the mechanism of intracellular signaling by ANG II stimulation in the adrenal, we have studied immediate-early regulated genes in human adrenal H295R cells using cDNA microarrays. H295R cells… CONTINUE READING
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