Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling.

@article{Guimares2011AngiotensinIB,
  title={Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling.},
  author={Paola Bianchi Guimar{\~a}es and {\'E}rika Costa Alvarenga and P. M. de Siqueira and Edgar Julian Paredes-Gamero and Regiane Ang{\'e}lica Sabatini and Rafael Leite Tavares de Morais and Rosana In{\'a}cio Dos Reis and Edson Lucas dos Santos and Luis Gustavo Deus Teixeira and Dulce E. Casarini and Renan Paulo Martin and Suma Imura Shimuta and Adriana Karaoglanovic Carmona and Cl{\'o}vis Ryuichi Nakaie and Miriam Galvonas Jasiulionis and Alice Teixeira Ferreira and Jorge Lu{\'i}s Pesquero and Suzana Macedo de Oliveira and Michael Bader and Cl{\'a}udio Miguel da Costa-Neto and Jo{\~a}o Bosco Pesquero},
  journal={Hypertension},
  year={2011},
  volume={57 5},
  pages={965-72}
}
Angiotensin (Ang) I-converting enzyme (ACE) is involved in the control of blood pressure by catalyzing the conversion of Ang I into the vasoconstrictor Ang II and degrading the vasodilator peptide bradykinin. Human ACE also functions as a signal transduction molecule, and the binding of ACE substrates or its inhibitors initiates a series of events. In this… CONTINUE READING