Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats.

@article{Casto1986AngiotensinIA,
  title={Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats.},
  author={Rod Casto and Michael Ian Phillips},
  journal={The American journal of physiology},
  year={1986},
  volume={250 2 Pt 2},
  pages={R193-8}
}
Microinjection of angiotensin II (ANG II) into the nucleus tractus solitarius (NTS) has been shown to produce a dose-dependent increase in blood pressure and heart rate. We have tested the effect of subpressor infusions of ANG II (10 ng . kg-1 . min-1) in the NTS on reflex bradycardia after intravenous administration of the vasoconstrictor phenylephrine (1-12 micrograms) in normotensive urethan-anesthetized rats. ANG II within the brain is thought to contribute to the decreased baroreflex… CONTINUE READING

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