Angiotensin II as a renal growth factor.

  title={Angiotensin II as a renal growth factor.},
  author={Gabrielle Wolf and Eric G. Neilson},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={3 9},
Angiotensin II (ANG II) can have multiple effects on the kidney, including influences on the regulation of glomerular hemodynamics and tubular transport as well as consequences for the glomerular processing of macromolecules. The recognized suppressive effects of angiotensin-converting enzyme inhibitors on compensatory renal growth, even in the absence of hemodynamic effects, and the well-documented proliferative effect of ANG II on vascular smooth muscle cells have provided the background for… CONTINUE READING