Angiotensin II and angiotensin 1–7: which is their role in atrial fibrillation?

  title={Angiotensin II and angiotensin 1–7: which is their role in atrial fibrillation?},
  author={A. Mascolo and K. Urbanek and A. Angelis and M. Sessa and C. Scavone and L. Berrino and G. Rosano and A. Capuano and F. Rossi},
  journal={Heart Failure Reviews},
  • A. Mascolo, K. Urbanek, +6 authors F. Rossi
  • Published 2019
  • Medicine
  • Heart Failure Reviews
  • Atrial fibrillation (AF) is a significant cause of morbidity and mortality as well as a public health burden considering the high costs of AF-related hospitalizations. Pre-clinical and clinical evidence showed a potential role of the renin angiotensin system (RAS) in the etiopathogenesis of AF. Among RAS mediators, angiotensin II (AII) and angiotensin 1–7 (A1–7) have been mostly investigated in AF. Specifically, the stimulation of the pathway mediated by AII or the inhibition of the pathway… CONTINUE READING
    5 Citations


    The Role Of Renin Angiotensin System In Atrial Fibrillation.
    • 13
    • PDF
    The role of the renin-angiotensin system in atrial fibrillation and the therapeutic effects of ACE-Is and ARBS.
    • 48
    Renin–angiotensin–aldosterone blockade reduces atrial fibrillation in hypertrophic cardiomyopathy
    • 10
    • Highly Influential
    The role of the renin-angiotensin system in the development of cardiovascular disease.
    • T. Unger
    • Medicine
    • The American journal of cardiology
    • 2002
    • 453
    The Impact of Suppressing the Renin‐Angiotensin System on Atrial Fibrillation
    • 54
    Prevention of atrial fibrillation with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: a meta-analysis.
    • 779