Angiotensin II and alpha-agonist. I. Responses of ovine fetoplacental vasculature.

@article{Yoshimura1990AngiotensinIA,
  title={Angiotensin II and alpha-agonist. I. Responses of ovine fetoplacental vasculature.},
  author={Toshihiro Yoshimura and Ronald R Magness and Charles R Rosenfeld},
  journal={The American journal of physiology},
  year={1990},
  volume={259 2 Pt 2},
  pages={H464-72}
}
During ovine pregnancy the uteroplacental vasculature is less responsive to angiotensin II (ANG II)-induced vasoconstriction than the systemic vasculature, whereas responses to alpha-agonists are just the opposite. Comparisons of fetal systemic and placental vascular responses to these agents are not well described, nor have they been compared with maternal responses. We determined steady-state responses to fetal infusions (5-7 min) of ANG II (0.023-5.73 micrograms/min) and phenylephrine (PHEN… CONTINUE READING