Angiotensin-II activation of cAMP and corticosterone production in bovine adrenocortical cells: effects of nonpeptide angiotensin-II antagonists.

@article{Rainey1991AngiotensinIIAO,
  title={Angiotensin-II activation of cAMP and corticosterone production in bovine adrenocortical cells: effects of nonpeptide angiotensin-II antagonists.},
  author={William E. Rainey and E William Byrd and R A Sinnokrot and Bruce Richard Carr},
  journal={Molecular and cellular endocrinology},
  year={1991},
  volume={81 1-3},
  pages={33-41}
}
The ability of angiotensin-II (A-II) to increase cAMP production in adrenocortical cells is not widely accepted due to numerous conflicting reports. The recent observation that rat adrenal cells exhibit multiple subtypes of A-II receptors raises the possibility that a specific subtype could be responsible for controlling cAMP stimulation. In the present study we characterize in detail the effects of A-II on cAMP production in bovine adrenocortical zona fasciculata cells (BAC) cells and… CONTINUE READING
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