Angiotensin II AT2 receptor subtype: an uprising frontier in cardiovascular disease?

@article{Volpe2003AngiotensinIA,
  title={Angiotensin II AT2 receptor subtype: an uprising frontier in cardiovascular disease?},
  author={Massimo Volpe and Beatrice Musumeci and Paola de Paolis and C. Blandin Savoia and Alberto Morganti},
  journal={Journal of hypertension},
  year={2003},
  volume={21 8},
  pages={
          1429-43
        }
}
The renin-angiotensin system (RAS) plays a pivotal role in the regulation of fluid, electrolyte balance and blood pressure, and is a modulator of cellular growth and proliferation. Biological actions of RAS are linked to the binding of the effector molecule, angiotensin II (AngII), to specific membrane receptors, mostly the AT1 subtype and, to a lesser extent, other subtypes. Following the identification and characterization of the AT2 subtype receptor, it has been proposed that a complex… CONTINUE READING
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