Angiotensin II, sympathetic nerve activity and chronic heart failure

@article{Wang2012AngiotensinIS,
  title={Angiotensin II, sympathetic nerve activity and chronic heart failure},
  author={Yutang Wang and Sai-wang Seto and Jonathan Golledge},
  journal={Heart Failure Reviews},
  year={2012},
  volume={19},
  pages={187-198}
}
Sympathetic nerve activity has been reported to be increased in both humans and animals with chronic heart failure. One of the mechanisms believed to be responsible for this phenomenon is increased systemic and cerebral angiotensin II signaling. Plasma angiotensin II is increased in humans and animals with chronic heart failure. The increase in angiotensin II signaling enhances sympathetic nerve activity through actions on both central and peripheral sites during chronic heart failure… CONTINUE READING
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