Angiotensin Converting Enzyme Inhibitors and Alzheimer Disease in the Presence of the Apolipoprotein E 4 Allele

@inproceedings{Qiu2014AngiotensinCE,
  title={Angiotensin Converting Enzyme Inhibitors and Alzheimer Disease in the Presence of the Apolipoprotein E 4 Allele},
  author={Wei Qiao Qiu and Angela Lai and Timothy Mon and Mkaya Mwamburi and Matthew Warren and Taylor and James L. Rosenzweig and Neil W. Kowall and Robert Stern and Haihao Zhu and David C. Steffens},
  year={2014}
}
Objective—The effect of angiotensin converting enzyme (ACE) inhibitors on Alzheimer disease (AD) remains unclear, with conflicting results reported. We studied the interaction of the Apolipoprotein E (ApoE) genotype and ACE inhibitors on AD. Methods—This was a cross-sectional study of homebound elderly with an AD diagnosis and documentation of medications taken. ApoE genotype was determined. Results—A total of 355 subjects with status on ApoE alleles and cognitive diagnoses were studied. The… CONTINUE READING
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