Angiotensin AT1 receptor-mediated vasopressin release and drinking are potentiated by an AT2 receptor antagonist.

@article{Hhle1995AngiotensinAR,
  title={Angiotensin AT1 receptor-mediated vasopressin release and drinking are potentiated by an AT2 receptor antagonist.},
  author={Stephanie H{\"o}hle and Heidi Spitznagel and Wolfgang Rascher and Juraj Culman and Thomas Unger},
  journal={European journal of pharmacology},
  year={1995},
  volume={275 3},
  pages={277-82}
}
Stimulation of angiotensin II AT2 receptors has been shown to inhibit AT1 receptor-mediated actions in peripheral tissues. The role of AT2 receptors in the central actions of angiotensin is not well understood. In the present study, plasma vasopressin levels and water intake in response to intracerebroventricular angiotensin II (10 pmol) were determined after intracerebroventricular pretreatment with PD 123177 (1-(4-amino-3-methylphenyl)methyl-5-diphenylacetyl-4,5,6,7-tetrahy dro-1H- imidazo[4… CONTINUE READING

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