Angiotensin AT1 receptor blockers suppress ischemia/reperfusion-induced gastric injury in rats

Abstract

Ischemia/reperfusion (I/R) damages gastric mucosa via reactive oxygen species (ROS) activity. ROS was reportedly produced through angiotensin II stimulation in tissues such as kidney, heart and brain. To determine whether AT1 receptor plays a role in gastric mucosal damage, we examined the effect of AT1 receptor blocker (ARB; losartan, candesartan… (More)
DOI: 10.1007/s10787-006-1551-3

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