Angiotensin-(1-7) reduces smooth muscle growth after vascular injury.

@article{Strawn1999Angiotensin17RS,
  title={Angiotensin-(1-7) reduces smooth muscle growth after vascular injury.},
  author={William B. Strawn and Carlos Maria Ferrario and E. Ann Tallant},
  journal={Hypertension},
  year={1999},
  volume={33 1 Pt 2},
  pages={
          207-11
        }
}
Regulation of vascular smooth muscle cell growth is critical to the maintenance of normal blood flow and vessel patency. Angiotensin-(1-7) [Ang-(1-7)] inhibits proliferation of vascular smooth muscle cells in vitro and opposes the mitogenic effects of angiotensin II. The present study investigated whether Ang-(1-7) inhibits vascular smooth muscle cell growth in vivo by determining its effect on neointimal formation and medial remodeling in balloon-injured carotid arteries. The carotid arteries… CONTINUE READING

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