Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen.

@article{Kangussu2013Angiotensin17AT,
  title={Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen.},
  author={Lucas Miranda Kangussu and Ana Fl{\'a}via Almeida-Santos and Michael Bader and Natalia Alenina and Marco Ant{\^o}nio Peliky Fontes and Robson Augusto Souza Santos and Daniele Cristina Aguiar and Maria Jos{\'e} Campagnole-Santos},
  journal={Behavioural brain research},
  year={2013},
  volume={257},
  pages={25-30}
}
Transgenic rats with low brain angiotensinogen, TGR(ASrAOGEN)680, expressing an antisense RNA against angiotensinogen in glial cells, provide an interesting tool to evaluate the role of brain angiotensins in different behavior responses. The present study was conducted to test the hypothesis that angiotensin-(1-7) [Ang-(1-7)] and serotonin can modulate anxiety and depression-related behaviors in the TGR(ASrAOGEN)680 rats. Therefore, the effect of acute intracerebroventricular administration of… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
3 Citations
8 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-8 of 8 references

Similar Papers

Loading similar papers…